(East Windsor,
NJ, USA) --- Magnus Precht, President of Phyton Biotech, Inc., has announced
the acquisition from The Dow Chemical Company of a novel, proprietary
technology and intellectual property platform for the engineering of
glycosylation in pharmaceutical protein products.
This acquisition will be enhanced through a research collaboration with
the Dutch research institute Plant Research International (PRI), part of
Wageningen University & Research Centre and one of the innovators of
the technology platform.
The announcement coincides with another milestone, the installation of
a second 75,000 liter bioreactor at Phyton’s German cell fermentation
facility.
“Our acquisition
and collaboration should be viewed vis-à-vis recent
developments in the glyco-engineering field, such as Merck’s acquisition
of GlycoFi and Roche’s acquisition of Glycart,” said Mr. Precht.
Dr. Laurence Korn, the co-founder and former CEO and Chairperson of PDL
(a leader in humanized antibodies) and an industry leader, stressed that
this technology complements the unique new protein expression platform
that Phyton is developing.
“The glyco-engineering
capability Phyton has acquired could allow the company to realize the full
potential of its plant cell fermentation expression
system,” said Dr. Korn, adding that Phyton plans to apply the technology
to humanizing glycosylation in monoclonal antibodies, a multi-billion dollar
market.
The glyco-engineering technology has the potential to diminish the clinical
effects of immunogenicity, optimize drug potency and increase drug half
life. For patients, a longer half life can mean less frequent injections.
Phyton is already a leader in plant cell fermentation technology, producing
paclitaxel for Bristol-Myers Squibb’s TAXOL® oncology product.
Phyton Biotech, Inc.,
is based in East Windsor, N.J. Phyton’s proprietary
plant cell culture technology platform is used to develop and manufacture
products with applications in the pharmaceutical and biotech industries.
Its German subsidiary, Phyton Biotech GmbH, operates the world’s
largest commercial cGMP manufacturing facility for plant cell fermentation.
Visit www.phytonbiotech.com.
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* Taxol is a registered trademark of Bristol-Myers Squibb Company.
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